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Multi-Modality Optical Imaging Salpingoscope for Early Cancer Detection |
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講者:Jennifer Barton 時間:2019/12/04 (三) 10:30~11:30
Advanced optical imaging techniques such as fluorescence imaging (FI), optical coherence tomography (OCT), and multiphoton microscopy (MPM) can be used for early detection of cancer in a miniature endoscopic system. We have developed a tri-modality 3.5 mm diameter endoscope with a single optical channel, plus channels for saline or fluorescent dye introduction, and biopsy forceps. The forward scanning illumination system consists of a quartered piezoelectric tube scanning a dual-clad single mode fiber. The core of the fiber carries visible illumination, OCT, and MPM excitation light. A telescope-like triplet lens and objective contain internal dichroic coatings such that the visible light is relayed to the tissue in a low numerical aperture (NA) broad field of view system, whereas the near-infrared OCT and MPM are relayed as high NA microscopy systems. Remitted light is collected in the fiber core (OCT), inner cladding (MPM), and separate multimode fibers (visible reflectance/FI). Predicted and actual optical performance will be presented.
主辦單位:臺大醫療器材與醫學影像研究所,臺大醫學院,科技部 協辦單位:臺大醫學院國際事務處,臺大永齡健康研究院
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