||Multi-Modality Optical Imaging Salpingoscope for Early Cancer Detection
2019/11/26 上午 11:07:03
時間:2019/12/04 （三） 10:30~11:30
Advanced optical imaging techniques such as fluorescence imaging （FI）, optical coherence tomography （OCT）, and multiphoton microscopy （MPM） can be used for early detection of cancer in a miniature endoscopic system. We have developed a tri-modality 3.5 mm diameter endoscope with a single optical channel, plus channels for saline or fluorescent dye introduction, and biopsy forceps. The forward scanning illumination system consists of a quartered piezoelectric tube scanning a dual-clad single mode fiber. The core of the fiber carries visible illumination, OCT, and MPM excitation light. A telescope-like triplet lens and objective contain internal dichroic coatings such that the visible light is relayed to the tissue in a low numerical aperture （NA） broad field of view system, whereas the near-infrared OCT and MPM are relayed as high NA microscopy systems. Remitted light is collected in the fiber core （OCT）, inner cladding （MPM）, and separate multimode fibers （visible reflectance/FI）. Predicted and actual optical performance will be presented.